PAR1 antibody (AA 42-102)

Catalog No. ABIN515442

Cited in 1 publication. The Mouse Monoclonal anti-PAR1 antibody (Clone 2C5) (ABIN515442) specifically detects PAR1 in WB, ELISA and PLA. The antibody is reactive with Human samples.

Quick Overview for PAR1 antibody (AA 42-102) (ABIN515442)

Target: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Proximity Ligation Assay (PLA)

Clone: 2C5

Product Details anti-PAR1 Antibody

Binding Specificity: AA 42-102

Purpose: Mouse monoclonal antibody raised against a partial recombinant F2R.

Sequence: SFLLRNPNDK YEPFWEDEEK NESGLTEYRL VSINKSSPLQ KQLPAFISED ASGYLTSSWL T

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: F2R (NP_001983.1, 42 a.a. ~ 102 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PAR1 antibody (ABIN515442)

Fazzini, DAntongiovanni, Giusti, Da Valle, Ciregia, Piano, Caputo, DUrsi, Gargini, Lucacchini, Mazzoni: "Altered protease-activated receptor-1 expression and signaling in a malignant pleural mesothelioma cell line, NCI-H28, with homozygous deletion of the ?-catenin gene." in: PLoS ONE, Vol. 9, Issue 11, pp. e111550, (2014) (PubMed).

Target Details for PAR1

Target: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Alternative Name: F2R

Background: Full Gene Name: coagulation factor II (thrombin) receptor
Synonyms: CF2R,HTR,PAR1,TR

Gene ID: 2149

NCBI Accession: NM_001992

Pathways: Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus