NBR1 antibody (AA 1-966)

Catalog No. ABIN517599

Cited in 2+ publications. The Mouse Polyclonal anti-NBR1 antibody (ABIN517599) specifically detects NBR1 in WB. The antibody is reactive with Human samples.

Quick Overview for NBR1 antibody (AA 1-966) (ABIN517599)

Target: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This NBR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NBR1 Antibody

Binding Specificity: AA 1-966

Purpose: Mouse polyclonal antibody raised against a full-length human NBR1 protein.

Sequence: MEPQVTLNVT FKNEIQSFLV SDPENTTWAD IEAMVKVSFD LNTIQIKYLD EENEEVSINS QGEYEEALKM AVKQGNQLQM QVHEGHHVVD EAPPPVVGAK RLAARAGKKP LAHYSSLVRV LGSDMKTPED PAVQSFPLVP CDTDQPQDKP PDWFTSYLET FREQVVNETV EKLEQKLHEK LVLQNPSLGS CPSEVSMPTS EETLFLPENQ FSWHIACNNC QRRIVGVRYQ CSLCPSYNIC EDCEAGPYGH DTNHVLLKLR RPVVGSSEPF CHSKYSTPRL PAALEQVRLQ KQVDKNFLKA EKQRLRAEKK QRKAEVKELK KQLKLHRKIH LWNSIHGLQS PKSPLGRPES LLQSNTLMLP LQPCTSVMPM LSAAFVDENL PDGTHLQPGT KFIKHWRMKN TGNVKWSADT KLKFMWGNLT LASTEKKDVL VPCLKAGHVG VVSVEFIAPA LEGTYTSHWR LSHKGQQFGP RVWCSIIVDP FPSEESPDNI EKGMISSSKT DDLTCQQEET FLLAKEERQL GEVTEQTEGT AACIPQKAKN VASERELYIP SVDLLTAQDL LSFELLDINI VQELERVPHN TPVDVTPCMS PLPHDSPLIE KPGLGQIEEE NEGAGFKALP DSMVSVKRKA ENIASVEEAE EDLSGTQFVC ETVIRSLTLD AAPDHNPPCR QKSLQMTFAL PEGPLGNEKE EIIHIAEEEA VMEEEEDEED EEEEDELKDE VQSQSSASSE DYIIILPECF DTSRPLGDSM YSSALSQPGL ERGAEGKPGV EAGQEPAEAG ERLPGGENQP QEHSISDILT TSQTLETVPL IPEVVELPPS LPRSSPCVHH HGSPGVDLPV TIPEVSSVPD QIRGEPRGSS GLVNSRQKSY DHSRHHHGSS IAGGLVKGAL SVAASAYKAL FAGPPVTAQP IISEDQTAAL MAHLFEMGFC DRQLNLRLLK KHNYNILQVV TELLQLNNND WYSQRY

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: NBR1 (NP_005890.2, 1 a.a. ~ 966 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-NBR1 antibody (ABIN517599)

Barnett, Liebl, Seymour, Gillen, Lim, Larock, Davies, Schulz, Nizet, Teasdale, Walker: "The globally disseminated M1T1 clone of group A Streptococcus evades autophagy for intracellular replication." in: Cell host & microbe, Vol. 14, Issue 6, pp. 675-82, (2013) (PubMed).

Kuo, Chen, Baron, Onder, Loewer, Almeida, Weismann, Xu, Houghton, Gao, Daley, Doxsey: "Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity." in: Nature cell biology, Vol. 13, Issue 10, pp. 1214-23, (2011) (PubMed).

Target Details for NBR1

Target: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Alternative Name: NBR1

Background: Full Gene Name: neighbor of BRCA1 gene 1
Synonyms: 1A1-3B,KIAA0049,M17S2,MIG19

Gene ID: 4077

NCBI Accession: NM_005899

Pathways: Autophagy