SMAD7 antibody (AA 160-260)

Catalog No. ABIN517666

This Mouse Monoclonal antibody specifically detects SMAD7 in WB, ELISA and IHC (p). It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for SMAD7 antibody (AA 160-260) (ABIN517666)

Target: SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SMAD7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1G10

Product Details anti-SMAD7 Antibody

Binding Specificity: AA 160-260

Purpose: Mouse monoclonal antibody raised against a partial recombinant SMAD7.

Sequence: CKVFRWPDLR HSSEVKRLCC CESYGKINPE LVCCNPHHLS RLCELESPPP PYSRYPMDFL KPTADCPDAV PSSAETGGTN YLAPGGLSDS QLLLEPGDRS H

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SMAD7 (NP_005895, 160 a.a. ~ 260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SMAD7 antibody (ABIN517666)

Aparecida-Silva, Borges, Kessler, Dias, Moreira, Kalil, Gutierrez: "Transforming growth factor-β1 SMAD effectors and medial cell number in ascending aorta diseases." in: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, Vol. 25, Issue 3, pp. 240-6, (2016) (PubMed).

Chen, Yang, Huang, Hsue, Lin et al.: "Aberrant expression in multiple components of the transforming growth factor-?1-induced Smad signaling pathway during 7,12-dimethylbenz[a]anthracene-induced hamster buccal-pouch squamous-cell ..." in: Oral oncology, Vol. 47, Issue 4, pp. 262-7, (2011) (PubMed).

Target Details for SMAD7

Target: SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))

Alternative Name: SMAD7

Background: Full Gene Name: SMAD family member 7
Synonyms: CRCS3,FLJ16482,MADH7,MADH8

Gene ID: 4092

NCBI Accession: NM_005904

Pathways: Interferon-gamma Pathway, Cell-Cell Junction Organization