Myosin 9 antibody (AA 131-220)

Catalog No. ABIN518147

There are 2+ publications for this product available. The Mouse Monoclonal anti-Myosin 9 antibody is suitable to detect Myosin 9 in samples from Human. It has been validated for WB, ELISA, IF and IHC (p).

Quick Overview for Myosin 9 antibody (AA 131-220) (ABIN518147)

Target: Myosin 9 (MYH9)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Myosin 9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4H3

Product Details anti-Myosin 9 Antibody

Binding Specificity: AA 131-220

Purpose: Mouse monoclonal antibody raised against a partial recombinant MYH9.

Sequence: RLKQLKRQLE EAEEEAQRAN ASRRKLQREL EDATETADAM NREVSSLKNK LRRGDLPFVV PRRMARKGAG DGSDEEVDGK ADGAEAKPAE

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: MYH9 (NP_002464.1, 1871 a.a. ~ 1960 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Myosin 9 antibody (ABIN518147)

Chiu, Chang, Huang, Chao, Hsu: "EGFR and myosin II inhibitors cooperate to suppress EGFR-T790M-mutant NSCLC cells." in: Molecular oncology, Vol. 6, Issue 3, pp. 299-310, (2012) (PubMed).

Betapudi, Gokulrangan, Chance, Egelhoff: "A proteomic study of myosin II motor proteins during tumor cell migration." in: Journal of molecular biology, Vol. 407, Issue 5, pp. 673-86, (2011) (PubMed).

Target Details for Myosin 9

Target: Myosin 9 (MYH9)

Alternative Name: MYH9

Background: Full Gene Name: myosin, heavy chain 9, non-muscle
Synonyms: DFNA17,EPSTS,FTNS,MGC104539,MHA,NMHC-II-A,NMMHCA

Gene ID: 4627

NCBI Accession: NM_002473

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Integrin Complex