PCCA antibody (AA 1-703)

Catalog No. ABIN518660

The Mouse Polyclonal anti-PCCA antibody has been validated for WB. It is suitable to detect PCCA in samples from Human. There are 2+ publications available.

Quick Overview for PCCA antibody (AA 1-703) (ABIN518660)

Target: PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This PCCA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PCCA Antibody

Binding Specificity: AA 1-703

Purpose: Mouse polyclonal antibody raised against a full-length human PCCA protein.

Sequence: MLSAALRTLK HVLYYSRQCL MVSRNLGSVG YDPNEKTFDK ILVANRGEIA CRVIRTCKKM GIKTVAIHSD VDASSVHVKM ADEAVCVGPA PTSKSYLNMD AIMEAIKKTR AQAVHPGYGF LSENKEFARC LAAEDVVFIG PDTHAIQAMG DKIESKLLAK KAEVNTIPGF DGVVKDAEEA VRIAREIGYP VMIKASAGGG GKGMRIAWDD EETRDGFRLS SQEAASSFGD DRLLIEKFID NPRHIEIQVL GDKHGNALWL NERECSIQRR NQKVVEEAPS IFLDAETRRA MGEQAVALAR AVKYSSAGTV EFLVDSKKNF YFLEMNTRLQ VEHPVTECIT GLDLVQEMIR VAKGYPLRHK QADIRINGWA VECRVYAEDP YKSFGLPSIG RLSQYQEPLH LPGVRVDSGI QPGSDISIYY DPMISKLITY GSDRTEALKR MADALDNYVI RGVTHNIALL REVIINSRFV KGDISTKFLS DVYPDGFKGH MLTKSEKNQL LAIASSLFVA FQLRAQHFQE NSRMPVIKPD IANWELSVKL HDKVHTVVAS NNGSVFSVEV DGSKLNVTST WNLASPLLSV SVDGTQRTVQ CLSREAGGNM SIQFLGTVYK VNILTRLAAE LNKFMLEKVT EDTSSVLRSP MPGVVVAVSV KPGDAVAEGQ EICVIEAMKM QNSMTAGKTG TVKSVHCQAG DTVGEGDLLV ELE

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: PCCA (AAH00140.1, 1 a.a. ~ 703 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PCCA antibody (ABIN518660)

Majtan, Kraus: "Folding and activity of mutant cystathionine ?-synthase depends on the position and nature of the purification tag: characterization of the R266K CBS mutant." in: Protein expression and purification, Vol. 82, Issue 2, pp. 317-24, (2012) (PubMed).

Chandler, Chandrasekaran, Carrillo-Carrasco, Senac, Hofherr, Barry, Venditti: "Adeno-associated virus serotype 8 gene transfer rescues a neonatal lethal murine model of propionic acidemia." in: Human gene therapy, Vol. 22, Issue 4, pp. 477-81, (2011) (PubMed).

Target Details for PCCA

Target: PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

Alternative Name: PCCA

Background: Full Gene Name: propionyl Coenzyme A carboxylase, alpha polypeptide
Synonyms:

Gene ID: 5095

Pathways: Monocarboxylic Acid Catabolic Process