LGMN antibody (AA 1-433)

Catalog No. ABIN519319

This Rabbit Polyclonal antibody specifically detects LGMN in WB. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for LGMN antibody (AA 1-433) (ABIN519319)

Target: LGMN (Legumain (LGMN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGMN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LGMN Antibody

Binding Specificity: AA 1-433

Purpose: Rabbit polyclonal antibody raised against a full-length human LGMN protein.

Sequence: MVWKVAVFLS VALGIGAVPI DDPEDGGKHW VVIVAGSNGW YNYRHQADAC HAYQIIHRNG IPDEQIVVMM YDDIAYSEDN PTPGIVINRP NGTDVYQGVP KDYTGEDVTP QNFLAVLRGD AEAVKGIGSG KVLKSGPQDH VFIYFTDHGS TGILVFPNED LHVKDLNETI HYMYKHKMYR KMVFYIEACE SGSMMNHLPD NINVYATTAA NPRESSYACY YDEKRSTYLG DWYSVNWMED SDVEDLTKET LHKQYHLVKS HTNTSHVMQY GNKTISTMKV MQFQGMKRKA SSPVPLPPVT HLDLTPSPDV PLTIMKRKLM NTNDLEESRQ LTEEIQRHLD ARHLIEKSVR KIVSLLAASE AEVEQLLSER APLTGHSCYP EALLHFRTHC FNWHSPTYEY ALRHLYVLVN LCEKPYPLHR IKLSMDHVCL GHY

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: LGMN (NP_001008530.1, 1 a.a. ~ 433 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-LGMN antibody (ABIN519319)

Garcia-Cattaneo, Gobert, Müller, Toscano, Flores, Lescure, Del Nery, Benaroch: "Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 23, pp. 9053-8, (2012) (PubMed).

Target Details for LGMN

Target: LGMN (Legumain (LGMN))

Alternative Name: LGMN

Background: Full Gene Name: legumain
Synonyms: AEP,LGMN1,PRSC1

Gene ID: 5641

NCBI Accession: NM_001008530

Pathways: Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades