Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

LGMN antibody

LGMN Reactivity: Human, Mouse, Rat IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7255373
  • Target See all LGMN Antibodies
    LGMN (Legumain (LGMN))
    Reactivity
    • 54
    • 24
    • 23
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 48
    • 7
    Rabbit
    Clonality
    • 49
    • 6
    Polyclonal
    Conjugate
    • 25
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LGMN antibody is un-conjugated
    Application
    • 47
    • 25
    • 14
    • 8
    • 8
    • 7
    • 2
    • 1
    • 1
    Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human LGMN (NP_001008530.1).
    Isotype
    IgG
    Top Product
    Discover our top product LGMN Primary Antibody
  • Application Notes
    IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    LGMN (Legumain (LGMN))
    Alternative Name
    LGMN (LGMN Products)
    Synonyms
    AEP antibody, LGMN1 antibody, PRSC1 antibody, AI746452 antibody, AU022324 antibody, Prsc1 antibody, MGC64351 antibody, cb173 antibody, cb460 antibody, sb:cb173 antibody, zgc:76953 antibody, wu:fa98g05 antibody, wu:fj92g08 antibody, lgmn antibody, MGC88980 antibody, DELTA VACUOLAR PROCESSING ENZYME antibody, DELTAVPE antibody, delta vacuolar processing enzyme antibody, legumain antibody, legumain L homeolog antibody, delta vacuolar processing enzyme antibody, Legumain antibody, LGMN antibody, Lgmn antibody, lgmn.L antibody, lgmn antibody, DELTA-VPE antibody, MBOO_RS07785 antibody, Odosp_3582 antibody, LOC569153 antibody
    Background
    This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform.
    Gene ID
    5641
    UniProt
    Q99538
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades
You are here:
Support