RAD51 antibody (AA 1-339)

Catalog No. ABIN519604

This Mouse Polyclonal antibody specifically detects RAD51 in WB and IHC (p). It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for RAD51 antibody (AA 1-339) (ABIN519604)

Target: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This RAD51 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RAD51 Antibody

Binding Specificity: AA 1-339

Purpose: Mouse polyclonal antibody raised against a full-length human RAD51 protein.

Sequence: MAMQMQLEAN ADTSVEEESF GPQPISRLEQ CGINANDVKK LEEAGFHTVE AVAYAPKKEL INIKGISEAK ADKILAEAAK LVPMGFTTAT EFHQRRSEII QITTGSKELD KLLQGGIETG SITEMFGEFR TGKTQICHTL AVTCQLPIDR GGGEGKAMYI DTEGTFRPER LLAVAERYGL SGSDVLDNVA YARAFNTDHQ TQLLYQASAM MVESRYALLI VDSATALYRT DYSGRGELSA RQMHLARFLR MLLRLADEFG VAVVITNQVV AQVDGAAMFA ADPKKPIGGN IIAHASTTRL YLRKGRGETR ICKIYDSPCL PEAEAMFAIN ADGVGDAKD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: RAD51 (NP_002866.2, 1 a.a. ~ 339 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-RAD51 antibody (ABIN519604)

Lesterlin, Ball, Schermelleh, Sherratt: "RecA bundles mediate homology pairing between distant sisters during DNA break repair." in: Nature, Vol. 506, Issue 7487, pp. 249-53, (2014) (PubMed).

Jeyasekharan, Liu, Hattori, Pisupati, Jonsdottir, Rajendra, Lee, Sundaramoorthy, Schlachter, Kaminski, Ofir-Rosenfeld, Sato, Savill, Ayoub, Venkitaraman: "A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization." in: Nature structural & molecular biology, Vol. 20, Issue 10, pp. 1191-8, (2013) (PubMed).

Target Details for RAD51

Target: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Alternative Name: RAD51

Background: Full Gene Name: RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
Synonyms: BRCC5,HRAD51,HsRad51,HsT16930,RAD51A,RECA

Gene ID: 5888

NCBI Accession: NM_002875

Pathways: DNA Damage Repair