TBCC antibody (AA 1-346)

Catalog No. ABIN520721

There are 3+ publications for this product available. The Mouse Monoclonal anti-TBCC antibody is suitable to detect TBCC in samples from Human. It has been validated for WB, ELISA and IF.

Quick Overview for TBCC antibody (AA 1-346) (ABIN520721)

Target: TBCC (Tubulin Folding Cofactor C (TBCC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TBCC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 3D3

Product Details anti-TBCC Antibody

Binding Specificity: AA 1-346

Purpose: Mouse monoclonal antibody raised against a full-length recombinant TBCC.

Sequence: MESVSCSAAA VRTGDMESQR DLSLVPERLQ RREQERQLEV ERRKQKRQNQ EVEKENSHFF VATFARERAA VEELLERAES VERLEEAASR LQGLQKLIND SVFFLAAYDL RQGQEALARL QAALAERRRG LQPKKRFAFK TRGKDAASST KVDAAPGIPP AVESIQDSPL PKKAEGDLGP SWVCGFSNLE SQVLEKRASE LHQRDVLLTE LSNCTVRLYG NPNTLRLTKA HSCKLLCGPV STSVFLEDCS DCVLAVACQQ LRIHSTKDTR IFLQVTSRAI VEDCSGIQFA PYTWSYPEID KDFESSGLDR SKNNWNDVDD FNWLARDMAS PNWSILPEEE RNIQWD

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: TBCC (AAH20170.1, 1 a.a. ~ 346 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-TBCC antibody (ABIN520721)

Hage-Sleiman, Herveau, Matera, Laurier, Dumontet: "Silencing of tubulin binding cofactor C modifies microtubule dynamics and cell cycle distribution and enhances sensitivity to gemcitabine in breast cancer cells." in: Molecular cancer therapeutics, Vol. 10, Issue 2, pp. 303-12, (2011) (PubMed).

Garcia-Mayoral, Castaño, Fanarraga, Zabala, Rico, Bruix: "The solution structure of the N-terminal domain of human tubulin binding cofactor C reveals a platform for tubulin interaction." in: PLoS ONE, Vol. 6, Issue 10, pp. e25912, (2011) (PubMed).

Hage-Sleiman, Herveau, Matera, Laurier, Dumontet: "Tubulin binding cofactor C (TBCC) suppresses tumor growth and enhances chemosensitivity in human breast cancer cells." in: BMC cancer, Vol. 10, pp. 135, (2010) (PubMed).

Target Details for TBCC

Target: TBCC (Tubulin Folding Cofactor C (TBCC))

Alternative Name: TBCC

Background: Full Gene Name: tubulin folding cofactor C
Synonyms: CFC

Gene ID: 6903