ATG5 antibody (AA 176-275)

Catalog No. ABIN522953

There is 1 publication for this product available. The Mouse Monoclonal anti-ATG5 antibody is suitable to detect ATG5 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for ATG5 antibody (AA 176-275) (ABIN522953)

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATG5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1G11

Product Details anti-ATG5 Antibody

Binding Specificity: AA 176-275

Purpose: Mouse monoclonal antibody raised against a partial recombinant ATG5.

Sequence: PAEENGFRYI PFRIYQTTTE RPFIQKLFRP VAADGQLHTL GDLLKEVCPS AIDPEDGEKK NQVMIHGIEP MLETPLQWLS EHLSYPDNFL HISIIPQPTD

Cross-Reactivity: Human, Mouse

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ATG5 (AAH02699, 176 a.a. ~ 275 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ATG5 antibody (ABIN522953)

Song, Zhang, Guo, Sun, Han, Li, Zhao, Deng, Xie, Zhang, Wu, Wei: "Autophagy contributes to the survival of CD133+ liver cancer stem cells in the hypoxic and nutrient-deprived tumor microenvironment." in: Cancer letters, Vol. 339, Issue 1, pp. 70-81, (2013) (PubMed).

Target Details for ATG5

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Alternative Name: ATG5

Background: Full Gene Name: ATG5 autophagy related 5 homolog (S. cerevisiae)
Synonyms: APG5,APG5-LIKE,APG5L,ASP,hAPG5

Gene ID: 9474

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy