PNKP antibody (AA 1-521)

Catalog No. ABIN524717

The Mouse Polyclonal anti-PNKP antibody has been validated for WB. It is suitable to detect PNKP in samples from Human. There is 1 publication available.

Quick Overview for PNKP antibody (AA 1-521) (ABIN524717)

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This PNKP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PNKP Antibody

Binding Specificity: AA 1-521

Purpose: Mouse polyclonal antibody raised against a full-length human PNKP protein.

Sequence: MGEVEAPGRL WLESPPGGAP PIFLPSDGQA LVLGRGPLTQ VTDRKCSRTQ VELVADPETR TVAVKQLGVN PSTTGTQELK PGLEGSLGVG DTLYLVNGLH PLTLRWEETR TPESQPDTPP GTPLVSQDEK RDAELPKKRM RKSNPGWENL EKLLVFTAAG VKPQGKVAGF DLDGTLITTR SGKVFPTGPS DWRILYPEIP RKLRELEAEG YKLVIFTNQM SIGRGKLPAE EFKAKVEAVV EKLGVPFQVL VATHAGLYRK PVTGMWDHLQ EQANDGTPIS IGDSIFVGDA AGRPANWAPG RKKKDFSCAD RLFALNLGLP FATPEEFFLK WPAAGFELPA FDPRTVSRSG PLCLPESRAL LSASPEVVVA VGFPGAGKST FLKKHLVSAG YVHVNRDTLG SWQRCVTTCE TALKQGKRVA IDNTNPDAAS RARYVQCARA AGVPCRCFLF TATLEQARHN NRFREMTDSS HIPVSDMVMY GYRKQFEAPT LAEGFSAILE IPFRLWVEPR LGRLYCQFSE G

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: PNKP (NP_009185, 1 a.a. ~ 521 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: No additive

Preservative: Without preservative

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PNKP antibody (ABIN524717)

Markkanen, Fischer, Ledentcova, Kessler, Dianov: "Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability." in: Nucleic acids research, Vol. 43, Issue 7, pp. 3667-79, (2015) (PubMed).

Target Details for PNKP

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Alternative Name: PNKP

Background: Full Gene Name: polynucleotide kinase 3'-phosphatase
Synonyms: PNK

Gene ID: 11284

NCBI Accession: NM_007254

Pathways: DNA Damage Repair, Nucleotide Phosphorylation