FAN1 antibody (AA 1-533)
This Mouse Polyclonal antibody specifically detects FAN1 in WB and IF. It exhibits reactivity toward Humanand has been mentioned in 1 publication.
Quick Overview for FAN1 antibody (AA 1-533) (ABIN524848)
Target
See all FAN1 Antibodies
FAN1
(FANCD2/FANCI-Associated Nuclease 1 (FAN1))
Reactivity
Human
Host
Mouse
Clonality
Polyclonal
Conjugate
This FAN1 antibody is un-conjugated
Application
Western Blotting (WB), Immunofluorescence (IF)
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Binding Specificity
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AA 1-533
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Purpose
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Mouse polyclonal antibody raised against a full-length human MTMR15 protein.
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Sequence
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MSEGKPPDKK KRPRRSLSIS KNKKKASNSI ISCFNNAPPA KLACPVCSKM VPRYDLNRHL DEMCANNDFV QVDPGQVGLI NSNVSMVDLT SVTLEDVTPK KSPPPKTNLT PGQSDSAKRE VKQKISPYFK SNDVVCKNQD ELRNRSVKVI CLGSLASKLS RKYVKAKKSI DKDEEFAGSS PQSSKSTVVK SLIDNSSEIE DEDQILENSS QKENVFKCDS LKEECIPEHM VRESKIMEAE SQKATRECEK SALTPGFSDN AIMLFSPDFT LRNTLKSTSE DSLVKQECIK EVVEKREACH CEEVKMTVAS EAKIQLSDSE AKSHSSADDA SAWSNIQEAP LQDDSCLNND IPHSIPLEQG SSCNGPGQTT GHPYYLRSFL VVLKTVLENE DDMLLFDEQE KGIVTKFYQL SATGQKLYVR LFQRKLSWIK MTKLEYEEIA LDLTPVIEEL TNAGFLQTES ELQELSEVLE LLSAPELKSL AKTFHLVNPN GQKQQLVDAF LKLAKQRSVC TWGKNKPGIG AVILKRFCWL LLQ
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Cross-Reactivity
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Human
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Characteristics
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Antibody reactive against mammalian transfected lysate.
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Immunogen
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MTMR15 (AAH47882.1, 1 a.a. ~ 533 a.a) full-length human protein.
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Application Notes
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Optimal working dilution should be determined by the investigator.
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Restrictions
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For Research Use only
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Buffer
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In 1x PBS, pH 7.4
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Handling Advice
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Aliquot to avoid repeated freezing and thawing.
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Storage
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-20 °C
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Storage Comment
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Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Sareen, Chaudhury, Adams, Sobeck: "Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase." in: Nucleic acids research, Vol. 40, Issue 17, pp. 8425-39, (2012) (PubMed).
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Target
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FAN1
(FANCD2/FANCI-Associated Nuclease 1 (FAN1))
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Alternative Name
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MTMR15
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Background
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Full Gene Name: myotubularin related protein 15
Synonyms: DKFZp451H236,DKFZp686K16147,KIAA1018
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Gene ID
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22909
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Pathways
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DNA Damage Repair
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