DKK1 antibody (AA 1-266)

Catalog No. ABIN524880

Cited in 6+ publications. The Mouse Monoclonal anti-DKK1 antibody (Clone 2A5) (ABIN524880) specifically detects DKK1 in WB, ELISA, IP and IHC (p). The antibody is reactive with Human samples.

Quick Overview for DKK1 antibody (AA 1-266) (ABIN524880)

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DKK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2A5

Product Details anti-DKK1 Antibody

Binding Specificity: AA 1-266

Purpose: Mouse monoclonal antibody raised against a full length recombinant DKK1.

Sequence: MMALGAAGAT RVSVAMVAAA LGGHPLLGVS ATLNSVLNSN AIKNLPPPLG GAAGHPGSAV SAAPGILYPG GNKYQTIDNY QPYPCAEDEE CGTDEYCASP TRGGDAGVQI CLACRKRRKR CMRHAMCCPG NYCKNGICVS SDQNHFRGEI EETITESFGN DHSTLDGYSR RTTLSSKMYH TTGQEGSVCL RSSDCASGLC CARHFWSKIC KPVLKGGQVC TKHRRKGSHG LEIFQRCYCG EGLSCRIQKD HHQASNSSRL HTCQRH

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: DKK1 (AAH01539.1, 1 a.a. ~ 266 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-DKK1 antibody (ABIN524880)

Yi, Liao, Li, Xie, Hu, Yi, Liu: "RNA interference-mediated targeting of DKK1 gene expression in Ishikawa endometrial carcinoma cells causes increased tumor cell invasion and migration." in: Oncology letters, Vol. 6, Issue 3, pp. 756-762, (2013) (PubMed).

Min, Lee, Kim, Park: "Genetic grouping of medulloblastomas by representative markers in pathologic diagnosis." in: Translational oncology, Vol. 6, Issue 3, pp. 265-72, (2013) (PubMed).

Taylor, Northcott, Korshunov, Remke, Cho, Clifford, Eberhart, Parsons, Rutkowski, Gajjar, Ellison, Lichter, Gilbertson, Pomeroy, Kool, Pfister: "Molecular subgroups of medulloblastoma: the current consensus." in: Acta neuropathologica, Vol. 123, Issue 4, pp. 465-72, (2012) (PubMed).

DAmelio, Roato, DAmico, Veneziano, Suman, Sassi, Bisignano, Ferracini, Gargiulo, Castoldi, Pescarmona, Isaia: "Bone and bone marrow pro-osteoclastogenic cytokines are up-regulated in osteoporosis fragility fractures." in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, Vol. 22, Issue 11, pp. 2869-77, (2011) (PubMed).

Shin, Rho, Jung, Han, Oh, Kim: "Carbonic anhydrase IX (CA9) modulates tumor-associated cell migration and invasion." in: Journal of cell science, Vol. 124, Issue Pt 7, pp. 1077-87, (2011) (PubMed).

Macdonald, Sales, Grant, Brown, Jabbour, Catalano: "Prokineticin 1 induces Dickkopf 1 expression and regulates cell proliferation and decidualization in the human endometrium." in: Molecular human reproduction, Vol. 17, Issue 10, pp. 626-36, (2011) (PubMed).

Target Details for DKK1

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Alternative Name: DKK1

Background: Full Gene Name: dickkopf homolog 1 (Xenopus laevis)
Synonyms: DKK-1,SK

Gene ID: 22943

Pathways: WNT Signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation