FAF2 antibody (AA 1-445)

Catalog No. ABIN525021

Cited in 3+ publications. The Mouse Polyclonal anti-FAF2 antibody (ABIN525021) specifically detects FAF2 in WB. The antibody is reactive with Human samples.

Quick Overview for FAF2 antibody (AA 1-445) (ABIN525021)

Target: FAF2 (Fas Associated Factor Family Member 2 (FAF2))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This FAF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FAF2 Antibody

Binding Specificity: AA 1-445

Purpose: Mouse polyclonal antibody raised against a full-length human UBXD8 protein.

Sequence: MAAPEERDLT QEQTEKLLQF QDLTGIESMD QCRHTLEQHN WNIEAAVQDR LNEQEGVPSV FNPPPSRPLQ VNTADHRIYS YVVSRPQPRG LLGWGYYLIM LPFRFTYYTI LDIFRFALRF IRPDPRSRVT DPVGDIVSFM HSFEEKYGRA HPVFYQGTYS QALNDAKREL RFLLVYLHGD DHQDSDEFCR NTLCAPEVIS LINTRMLFWA CSTNKPEGYR VSQALRENTY PFLAMIMLKD RRMTVVGRLE GLIQPDDLIN QLTFIMDANQ TYLVSERLER EERNQTQVLR QQQDEAYLAS LRADQEKERK KREERERKRR KEEEVQQQKL AEERRRQNLQ EEKERKLECL PPEPSPDDPE SVKIIFKLPN DSRVERRFHF SQSLTVIHDF LFSLKESPEK FQIEANFPRR VLPCIPSEEW PNPPTLQEAG LSHTEVLFVQ DLTDE

Cross-Reactivity: Human, Rat

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: UBXD8 (NP_055428.1, 1 a.a. ~ 445 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: No additive

Preservative: Without preservative

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-FAF2 antibody (ABIN525021)

Jo, Hartman, DeBose-Boyd: "Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes." in: Molecular biology of the cell, Vol. 24, Issue 3, pp. 169-83, (2013) (PubMed).

Jo, Lee, Sguigna, DeBose-Boyd: "Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 51, pp. 20503-8, (2011) (PubMed).

Lee, Zhang, Feramisco, Gong, Ye: "Unsaturated fatty acids inhibit proteasomal degradation of Insig-1 at a postubiquitination step." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33772-83, (2008) (PubMed).

Target Details for FAF2

Target: FAF2 (Fas Associated Factor Family Member 2 (FAF2))

Alternative Name: FAF2

Background: Full Gene Name: Fas associated factor family member 2
Synonyms: ETEA,KIAA0887,UBXD8,UBXN3B

Gene ID: 23197

NCBI Accession: NM_014613