desert Hedgehog antibody (AA 1-396)

Catalog No. ABIN526347

Cited in 1 publication. The Mouse Polyclonal anti-desert Hedgehog antibody (ABIN526347) specifically detects desert Hedgehog in WB. The antibody is reactive with Human samples.

Quick Overview for desert Hedgehog antibody (AA 1-396) (ABIN526347)

Target: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This desert Hedgehog antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-desert Hedgehog Antibody

Binding Specificity: AA 1-396

Purpose: Mouse polyclonal antibody raised against a full-length human DHH protein.

Sequence: MALLTNLLPL CCLALLALPA QSCGPGRGPV GRRRYARKQL VPLLYKQFVP GVPERTLGAS GPAEGRVARG SERFRDLVPN YNPDIIFKDE ENSGADRLMT ERCKERVNAL AIAVMNMWPG VRLRVTEGWD EDGHHAQDSL HYEGRALDIT TSDRDRNKYG LLARLAVEAG FDWVYYESRN HVHVSVKADN SLAVRAGGCF PGNATVRLWS GERKGLRELH RGDWVLAADA SGRVVPTPVL LFLDRDLQRR ASFVAVETEW PPRKLLLTPW HLVFAARGPA PAPGDFAPVF ARRLRAGDSV LAPGGDALRP ARVARVAREE AVGVFAPLTA HGTLLVNDVL ASCYAVLESH QWAHRAFAPL RLLHALGALL PGGAVQPTGM HWYSRLLYRL AEELLG

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: DHH (NP_066382.1, 1 a.a. ~ 396 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-desert Hedgehog antibody (ABIN526347)

McKee, Xu, Cao, Kabraji, Allen, Kersemans, Beech, Smart, Hamdy, Ishkanian, Sykes, Pintile, Milosevic, van der Kwast, Zafarana, Ramnarine, Jurisica, Mallof, Lam, Bristow, Muschel: "Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma." in: The Journal of clinical investigation, Vol. 122, Issue 11, pp. 4025-36, (2012) (PubMed).

Target Details for desert Hedgehog

Target: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Alternative Name: DHH

Target Type: Species

Background: Full Gene Name: desert hedgehog homolog (Drosophila)
Synonyms: HHG-3,MGC35145

Gene ID: 50846

NCBI Accession: NM_021044

Pathways: Hedgehog Signaling