UGT1A9 antibody (AA 1-530)

Catalog No. ABIN527130

Cited in 2+ publications. The Mouse Polyclonal anti-UGT1A9 antibody (ABIN527130) specifically detects UGT1A9 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for UGT1A9 antibody (AA 1-530) (ABIN527130)

Target: UGT1A9 (UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This UGT1A9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-UGT1A9 Antibody

Binding Specificity: AA 1-530

Purpose: Mouse polyclonal antibody raised against a full-length human UGT1A9 protein.

Sequence: MACTGWTSPL PLCVCLLLTC GFAEAGKLLV VPMDGSHWFT MRSVVEKLIL RGHEVVVVMP EVSWQLGRSL NCTVKTYSTS YTLEDLDREF KAFAHAQWKA QVRSIYSLLM GSYNDIFDLF FSNCRSLFKD KKLVEYLKES SFDAVFLDPF DNCGLIVAKY FSLPSVVFAR GILCHYLEEG AQCPAPLSYV PRILLGFSDA MTFKERVRNH IMHLEEHLLC HRFFKNALEI ASEILQTPVT EYDLYSHTSI WLLRTDFVLD YPKPVMPNMI FIGGINCHQG KPLPMEFEAY INASGEHGIV VFSLGSMVSE IPEKKAMAIA DALGKIPQTV LWRYTGTRPS NLANNTILVK WLPQNDLLGH PMTRAFITHA GSHGVYESIC NGVPMVMMPL FGDQMDNAKR METKGAGVTL NVLEMTSEDL ENALKAVIND KSYKENIMRL SSLHKDRPVE PLDLAVFWVE FVMRHKGAPH LRPAAHDLTW YQYHSLDVIG FLLAVVLTVA FITFKCCAYG YRKCLGKKGR VKKAHKSKTH

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: UGT1A9 (NP_066307.1, 1 a.a. ~ 530 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-UGT1A9 antibody (ABIN527130)

Wang, Bian, Jin, Chen, Lin, Chen: "Association analysis of UGT1A genotype and haplotype with SN-38 glucuronidation in human livers." in: Pharmacogenomics, Vol. 15, Issue 6, pp. 785-98, (2014) (PubMed).

Hardwick, Ferreira, More, Lake, Lu, Manautou, Slitt, Cherrington: "Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 41, Issue 3, pp. 554-61, (2013) (PubMed).

Target Details for UGT1A9

Target: UGT1A9 (UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9))

Alternative Name: UGT1A9

Background: Full Gene Name: UDP glucuronosyltransferase 1 family, polypeptide A9
Synonyms: HLUGP4,LUGP4,UDPGT,UGT1AI

Gene ID: 54600

NCBI Accession: NM_021027

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha