UGT1A9 antibody (AA 26-250)

Catalog No. ABIN3022343

The Rabbit Polyclonal anti-UGT1A9 antibody (ABIN3022343) specifically detects UGT1A9 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for UGT1A9 antibody (AA 26-250) (ABIN3022343)

Target: UGT1A9 (UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGT1A9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-UGT1A9 Antibody

Binding Specificity: AA 26-250

Sequence: GKLLVVPMDG SHWFTMRSVV EKLILRGHEV VVVMPEVSWQ LGRSLNCTVK TYSTSYTLED LDREFKAFAH AQWKAQVRSI YSLLMGSYND IFDLFFSNCR SLFKDKKLVE YLKESSFDAV FLDPFDNCGL IVAKYFSLPS VVFARGILCH YLEEGAQCPA PLSYVPRILL GFSDAMTFKE RVRNHIMHLE EHLLCHRFFK NALEIASEIL QTPVTEYDLY SHTSI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-250 of human UGT1A9 (NP_066307.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UGT1A9

Target: UGT1A9 (UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9))

Alternative Name: UGT1A9

Background: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols.,UGT1A9,HLUGP4,LUGP4,UDPGT,UDPGT 1-9,UGT-1I,UGT1-09,UGT1-9,UGT1.9,UGT1A9S,UGT1AI,UGT1I,UDPGT1-9,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Drug metabolism,UGT1A9

Molecular Weight: 49 kDa/59 kDa

Gene ID: 54600

UniProt: O60656

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha