TLE6 antibody (AA 1-449)

Catalog No. ABIN529072

This Mouse Monoclonal antibody specifically detects TLE6 in WB and ELISA. It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for TLE6 antibody (AA 1-449) (ABIN529072)

Target: TLE6 (Transducin-Like Enhancer of Split 6 (TLE6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLE6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2E4

Product Details anti-TLE6 Antibody

Binding Specificity: AA 1-449

Purpose: Mouse monoclonal antibody raised against a full length recombinant TLE6.

Sequence: MATRSSDWLR RPLGEDNQPE TQLFWDKEPW FWHDTLTEQL WRIFAGVHDE KAKPRDRQQA PGLGQESKAP GSCDPGTDPC PEDASTPRPP EASSSPPEGS QDRNTSWGVV QEPPGRASRF LQSISWDPED FEDAWKRPDA LPGQSKRLAV PCKLEKMRIL AHGELVLATA ISSFTRHVFT CGRRGIKVWS LTGQVAEDRF PESHLPIQTP GAFLRTCLLS SNSRSLLTGG YNLASVSVWD LAAPSLHVKE QLPCAGLNCQ ALDANLDANL AFASFTSGVV RIWDLRDQSV VRDLKGYPDG VKSIVVKGYN IWTGGPDACL RCWDQRTIMK PLEYQFKSQI MSLSHSPQED WVLLGMANGQ QWLQSTSGSQ RHMVGQKDSV ILSVKFSPFG QWWASVGMDD FLGVYSMPAG TKVFEVPEMS PVTCCDVSSN NRLVVTGSGE HASVYQITY

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: TLE6 (AAH20206, 1 a.a. ~ 449 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-TLE6 antibody (ABIN529072)

Verginelli, Perin, Dali, Fung, Lo, Longatti, Guiot, Del Maestro, Rossi, di Porzio, Stechishin, Weiss, Stifani: "Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth." in: Nature communications, Vol. 4, pp. 2956, (2013) (PubMed).

Target Details for TLE6

Target: TLE6 (Transducin-Like Enhancer of Split 6 (TLE6))

Alternative Name: TLE6

Background: Full Gene Name: transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
Synonyms: FLJ14009,GRG6,MGC14966

Gene ID: 79816

Pathways: WNT Signaling