FGD5 antibody (AA 1-540)
This Mouse Polyclonal antibody specifically detects FGD5 in WB. It exhibits reactivity toward Human and has been mentioned in 2+ publications.
Quick Overview for FGD5 antibody (AA 1-540) (ABIN531046)
Target
See all FGD5 Antibodies
FGD5
(FYVE, RhoGEF and PH Domain Containing 5 (FGD5))
Reactivity
Human
Host
Mouse
Clonality
Polyclonal
Conjugate
This FGD5 antibody is un-conjugated
Application
Western Blotting (WB)
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Binding Specificity
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AA 1-540
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Purpose
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Mouse polyclonal antibody raised against a full-length human FGD5 protein.
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Sequence
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MRALDDMDHE GRDTLAREEL RQGLSELPAI HDLHQGILEE LEERLSNWES QQKVADVFLA REQGFDHHAT HILQFDRYLG LLSENCLHSP RLAAAVREFE QSVQGGSQTA KHRLLRVVQR LFQYQVLLTD YLNNLCPDSA EYDNTQGALS LISKVTDRAN DSMEQGENLQ KLVHIEHSVR GQGDLLQPGR EFLKEGTLMK VTGKNRRPRH LFLMNDVLLY TYPQKDGKYR LKNTLAVANM KVSRPVMEKV PYALKIETSE SCLMLSASSC AERDEWYGCL SRALPEDYKA QALAAFHHSV EIRERLGVSL GERPPTLVPV THVMMCMNCG CDFSLTLRRH HCHACGKIVC RNCSRNKYPL KYLKDRMAKV CDGCFGELKK RGRAVPGLMR ERPVSMSFPL SSPRFSGSAF SSVFQSINPS TFKKQKKVPS ALTEVAASGE GSAISGYLSR CKRGKRHWKK LWFVIKGKVL YTYMASEDKV ALESMPLLGF TIAPEKEEGS SEVGPIFHLY HKKTLFYSFK AEDTNSAQRW IEAMEDASVL
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Cross-Reactivity
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Human
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Characteristics
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Antibody reactive against mammalian transfected lysate.
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Immunogen
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FGD5 (AAH35364.1, 1 a.a. ~ 540 a.a) full-length human protein.
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Application Notes
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Optimal working dilution should be determined by the investigator.
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Restrictions
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For Research Use only
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Buffer
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In 1x PBS, pH 7.4
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Handling Advice
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Aliquot to avoid repeated freezing and thawing.
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Storage
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-20 °C
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Storage Comment
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Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Ando, Fukuhara, Moriya, Obara, Nakahata, Mochizuki: "Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization." in: The Journal of cell biology, Vol. 202, Issue 6, pp. 901-16, (2013) (PubMed).
Kurogane, Miyata, Kubo, Nagamatsu, Kundu, Uemura, Ishida, Quertermous, Hirata, Rikitake: "FGD5 mediates proangiogenic action of vascular endothelial growth factor in human vascular endothelial cells." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 32, Issue 4, pp. 988-96, (2012) (PubMed).
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Target
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FGD5
(FYVE, RhoGEF and PH Domain Containing 5 (FGD5))
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Alternative Name
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FGD5
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Background
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Full Gene Name: FYVE, RhoGEF and PH domain containing 5
Synonyms: ZFYVE23
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Gene ID
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152273
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