AT1A1 antibody (N-Term)

Catalog No. ABIN5514385

The Rabbit Polyclonal anti-AT1A1 antibody is suitable to detect AT1A1 in samples from Human. It has been validated for WB.

Quick Overview for AT1A1 antibody (N-Term) (ABIN5514385)

Target: AT1A1 (Sodium/potassium-Transporting ATPase Subunit alpha-1 (AT1A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB)

Product Details anti-AT1A1 Antibody

Binding Specificity: N-Term

Sequence: GRDKYEPAAV SEQGDKKGKK GKKDRDMDEL KKEVSMDDHK LSLDELHRKY

Characteristics: This is a rabbit polyclonal antibody against AT1A1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human AT1A1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AT1A1

Target: AT1A1 (Sodium/potassium-Transporting ATPase Subunit alpha-1 (AT1A1))

Alternative Name: AT1A1

Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: ATP1A1,

Protein Size: 1023

Gene ID: 476

UniProt: P05023