Bystin-Like antibody (N-Term)

Catalog No. ABIN5514386

The Rabbit Polyclonal anti-Bystin-Like antibody (ABIN5514386) specifically detects Bystin-Like in WB. The antibody is reactive with Human samples.

Quick Overview for Bystin-Like antibody (N-Term) (ABIN5514386)

Target: Bystin-Like (BYSL)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Bystin-Like antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Bystin-Like Antibody

Binding Specificity: N-Term

Purpose: BYSL Antibody - N-terminal region

Sequence: RGTGEAEEEY VGPRLSRRIL QQARQQQEEL EAEHGTGDKP AAPRERTTRL

Characteristics: This is a rabbit polyclonal antibody against BYST. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human BYST

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60059-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Bystin-Like

Target: Bystin-Like (BYSL)

Alternative Name: BYSL

Background:

Background Information: Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy. Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi.

Gene Name: bystin like

Alternative Symbols: Enp1, BYSTIN

Protein Name: bystin

Molecular Weight: 48kDa

Gene ID: 705

NCBI Accession: NP_004044

UniProt: Q13895

Pathways: Cellular Response to Molecule of Bacterial Origin