CD2BP2 antibody (C-Term)

Catalog No. ABIN5514387

This Rabbit Polyclonal antibody specifically detects CD2BP2 in WB. It exhibits reactivity toward Human.

Quick Overview for CD2BP2 antibody (C-Term) (ABIN5514387)

Target: CD2BP2 (CD2 (Cytoplasmic Tail) Binding Protein 2 (CD2BP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD2BP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD2BP2 Antibody

Binding Specificity: C-Term

Sequence: DAELYGPFTS AQMQTWVSEG YFPDGVYCRK LDPPGGQFYN SKRIDFDLYT

Characteristics: This is a rabbit polyclonal antibody against CD2B2. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CD2B2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD2BP2

Target: CD2BP2 (CD2 (Cytoplasmic Tail) Binding Protein 2 (CD2BP2))

Alternative Name: CD2B2

Background: This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.

Alias Symbols: CD2BP2, KIAA1178,

Protein Interaction Partner: SNRPB, PPP1CC, USP19, UBC, PPP1CA, CSNK2A1, SMU1, PRPF6, PAXIP1, PRPF8, SNRNP40, UBE2V2, SNRPF, SH3BGRL, SGTA, S100A9, S100A6, RAB5B, PSMD9, PLP2, GINS4, TBL1XR1, GINS3, EP400, UBQLN4, POMP, COTL1, MGA, SNRNP200, AHCYL1, AKNA, WBP11, PSMF1, CUL3, CD2, SF3

Protein Size: 341

Gene ID: 10421

NCBI Accession: NP_006101

UniProt: O95400

Pathways: Ribonucleoprotein Complex Subunit Organization