ELOVL1 antibody (N-Term)

Catalog No. ABIN5514396

Product Details anti-ELOVL1 Antibody

Target: ELOVL1 (ELOVL Fatty Acid Elongase 1 (ELOVL1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Cow, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELOVL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RGFMIVYNFS LVALSLYIVY EFLMSGWLST YTWRCDPVDY SNSPEALRMV

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against ELOV1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ELOV1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ELOVL1

Target: ELOVL1 (ELOVL Fatty Acid Elongase 1 (ELOVL1))

Alternative Name: ELOV1 (ELOVL1 Products)

Synonyms: AA407424 antibody, BB151133 antibody, Ssc1 antibody, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 antibody, ELOVL fatty acid elongase 1 antibody, Elovl1 antibody, ELOVL1 antibody

Background: ELOV1 is a condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids (VLCFAs). It exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. It is important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.

Alias Symbols: ELOVL1, SSC1, CGI-88,

Protein Interaction Partner: UBC, HSD17B12, CERS2, TECR, GLP1R, TWF2, PSMD10,

Protein Size: 279

Gene ID: 64834

NCBI Accession: NP_073732

UniProt: Q9BW60