MARH8 antibody (N-Term)

Catalog No. ABIN5514406

The Rabbit Polyclonal anti-MARH8 antibody has been validated for WB. It is suitable to detect MARH8 in samples from Human.

Quick Overview for MARH8 antibody (N-Term) (ABIN5514406)

Target: MARH8 (e3 Ubiquitin-Protein Ligase 8-Mar (MARH8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB)

Product Details anti-MARH8 Antibody

Binding Specificity: N-Term

Sequence: MSMPLHQISA IPSQDAISAR VYRSKTKEKE REEQNEKTLG HFMSHSSNIS

Characteristics: This is a rabbit polyclonal antibody against MARH8. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MARH8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MARH8

Target: MARH8 (e3 Ubiquitin-Protein Ligase 8-Mar (MARH8))

Alternative Name: MARH8

Background: MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins.

Alias Symbols: MARCH8, MIR, RNF178,

Protein Interaction Partner: TNFRSF10A, UBC, UBE2H, UBE2D1, TFRC, UBE2D3, IL1RAP, IL1R1, CD86,

Protein Size: 291

Gene ID: 220972

UniProt: Q5T0T0