MARH8 antibody

Catalog No. ABIN7229572

This Rabbit Polyclonal antibody specifically detects MARH8 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for MARH8 antibody (ABIN7229572)

Target: MARH8 (e3 Ubiquitin-Protein Ligase 8-Mar (MARH8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARH8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MARH8 Antibody

Purpose: Rabbit Anti-MARH8 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MARH8 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MARH8 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MARH8

Target: MARH8 (e3 Ubiquitin-Protein Ligase 8-Mar (MARH8))

Alternative Name: MARH8

Background: E3 ubiquitin-protein ligase MARCH8, Cellular modulator of immune recognition, c-MIR, Membrane-associated RING finger protein 8, Membrane-associated RING-CH protein VIII, MARCH-VIII, RING finger protein 178, RING-type E3 ubiquitin transferase MARCH8MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins. MARCH8 (Membrane Associated Ring-CH-Type Finger 8) is a Protein Coding gene.

Molecular Weight: 32kD

Gene ID: 220972

UniProt: Q5T0T0