TCOF1 antibody (N-Term)

Catalog No. ABIN5514428

The Rabbit Polyclonal anti-TCOF1 antibody (ABIN5514428) specifically detects TCOF1 in WB. The antibody is reactive with Human samples.

Quick Overview for TCOF1 antibody (N-Term) (ABIN5514428)

Target: TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCOF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TCOF1 Antibody

Binding Specificity: N-Term

Purpose: TCOF1 Antibody - N-terminal region

Sequence: MAEARKRREL LPLIYHHLLR AGYVRAAREV KEQSGQKCFL AQPVTLLDIY

Characteristics: This is a rabbit polyclonal antibody against TCOF. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TCOF

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75152-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TCOF1

Target: TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))

Alternative Name: TCOF1

Background:

Background Information: This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: treacle ribosome biogenesis factor 1

Alternative Symbols: TCS, MFD1, TCS1, treacle

Protein Name: treacle protein

Molecular Weight: 155kDa

Gene ID: 6949

UniProt: Q13428