Treacle Protein antibody (N-Term)
Quick Overview for Treacle Protein antibody (N-Term) (ABIN5514428)
Target
Reactivity
Host
Clonality
Application
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Binding Specificity
- N-Term
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Sequence
- MAEARKRREL LPLIYHHLLR AGYVRAAREV KEQSGQKCFL AQPVTLLDIY
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Characteristics
- This is a rabbit polyclonal antibody against TCOF. It was validated on Western Blot.
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Purification
- Affinity purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human TCOF
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Treacle Protein (TCOF)
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Alternative Name
- TCOF
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Background
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This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: TCOF1,
Protein Size: 1411 -
Gene ID
- 6949
Target
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