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TTHY antibody (N-Term)

TTHY Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5514452
  • Target See all TTHY products
    TTHY (Thymocyte Alloantigen (TTHY))
    Binding Specificity
    N-Term
    Reactivity
    Human
    Host
    Rabbit
    Clonality
    Polyclonal
    Application
    Western Blotting (WB)
    Sequence
    CPLMVKVLDA VRGSPAINVA VHVFRKAADD TWEPFASGKT SESGELHGLT
    Characteristics
    This is a rabbit polyclonal antibody against TTHY. It was validated on Western Blot.
    Purification
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human TTHY
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TTHY (Thymocyte Alloantigen (TTHY))
    Alternative Name
    TTHY (TTHY Products)
    Synonyms
    thymocyte alloantigen antibody, Tthy antibody
    Background
    This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

    Alias Symbols: TTR, PALB,

    Protein Size: 147
    Gene ID
    7276
    NCBI Accession
    NP_000362
    UniProt
    P02766
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