TTHY antibody (N-Term)
The Rabbit Polyclonal anti-TTHY antibody (ABIN5514452) specifically detects TTHY in WB.
The antibody is reactive with Human samples.
Catalog No. ABIN5514452
$483.54
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Quick Overview for TTHY antibody (N-Term) (ABIN5514452)
Target
TTHY
(Thymocyte Alloantigen (TTHY))
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Application
Western Blotting (WB)
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Binding Specificity
- N-Term
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Sequence
- CPLMVKVLDA VRGSPAINVA VHVFRKAADD TWEPFASGKT SESGELHGLT
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Characteristics
- This is a rabbit polyclonal antibody against TTHY. It was validated on Western Blot.
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Purification
- Affinity purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human TTHY
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TTHY (Thymocyte Alloantigen (TTHY))
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Alternative Name
- TTHY
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Background
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This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
Alias Symbols: TTR, PALB,
Protein Size: 147 -
Gene ID
- 7276
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NCBI Accession
- NP_000362
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UniProt
- P02766
Target
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