HNRNPA1 antibody (C-Term)

Catalog No. ABIN5514461

The Rabbit Polyclonal anti-HNRNPA1 antibody (ABIN5514461) specifically detects HNRNPA1 in WB. The antibody is reactive with Human samples.

Quick Overview for HNRNPA1 antibody (C-Term) (ABIN5514461)

Target: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HNRNPA1 Antibody

Binding Specificity: C-Term

Purpose: HNRNPA1 Antibody - C-terminal region

Sequence: GSGYGGSGSY DSYNNGGGGG FGGGSGSNFG GGGSYNDFGN YNNQSSNFGP

Characteristics: This is a rabbit polyclonal antibody against ROA1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ROA1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP76272-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HNRNPA1

Target: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Alternative Name: HNRNPA1

Background:

Background Information: This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome.

Gene Name: heterogeneous nuclear ribonucleoprotein A1

Alternative Symbols: UP 1, ALS19, ALS20, HNRPA1, IBMPFD3, HNRPA1L3, hnRNP A1, hnRNP-A1

Protein Name: heterogeneous nuclear ribonucleoprotein A1

Molecular Weight: 39kDa

Gene ID: 3178

NCBI Accession: XP_005268883

UniProt: P09651