NCEH1 antibody (C-Term)

Catalog No. ABIN5514478

The Rabbit Polyclonal anti-NCEH1 antibody is suitable to detect NCEH1 in samples from Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig and Rabbit. It has been validated for WB.

Quick Overview for NCEH1 antibody (C-Term) (ABIN5514478)

Target: NCEH1 (Neutral Cholesterol Ester Hydrolase 1 (NCEH1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCEH1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NCEH1 Antibody

Binding Specificity: C-Term

Purpose: NCEH1 Antibody - C-terminal region

Sequence: GIMYAKRLES AGVEVTLDHF EDGFHGCMIF TSWPTNFSVG IRTRNSYIKW

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NCEH1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NCEH1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49570-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NCEH1

Target: NCEH1 (Neutral Cholesterol Ester Hydrolase 1 (NCEH1))

Alternative Name: NCEH1

Background:

Background Information: NCEH1 hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. It may be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. NCEH1 also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. It may contribute to cancer pathogenesis by promoting tumor cell migration.

Gene Name: neutral cholesterol ester hydrolase 1

Alternative Symbols: NCEH, AADACL1

Protein Name: Neutral cholesterol ester hydrolase 1

Molecular Weight: 30kDa

Gene ID: 57552

UniProt: Q6PIU2