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ANAPC5 antibody (Middle Region)
ANAPC5
Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ANAPC5 Antibody
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Target
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ANAPC5
(Anaphase Promoting Complex Subunit 5 (ANAPC5))
Binding Specificity
All epitopes for ANAPC5 antibodies
Middle Region
Reactivity
All reactivities for ANAPC5 antibodies
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio)
Host
All hosts for ANAPC5 antibodies
Rabbit
Clonality
All clonalities for ANAPC5 antibodies
Polyclonal
Conjugate
All conjugates for ANAPC5 antibodies
This ANAPC5 antibody is un-conjugated
Application
All applications for ANAPC5 antibodies
Western Blotting (WB)
Sequence
HSLLHYFDRL ILTGAESKSN GEEGYGRSLR YAALNLAALH CRFGHYTSPP
Predicted Reactivity
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
Characteristics
This is a rabbit polyclonal antibody against ANAPC5. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human ANAPC5
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for ANAPC5
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Target
ANAPC5
(Anaphase Promoting Complex Subunit 5 (ANAPC5))
Alternative Name
ANAPC5 (ANAPC5 Products )
Synonyms
APC5 antibody, DDBDRAFT_0206386 antibody, DDBDRAFT_0234269 antibody, DDB_0206386 antibody, DDB_0234269 antibody, zgc:55800 antibody, wu:fb75a09 antibody, ANAPC5 antibody, MGC89697 antibody, 2510006G12Rik antibody, AA408751 antibody, AA536819 antibody, AA986414 antibody, Anpc5 antibody, F12K11.7 antibody, F12K11_7 antibody, anaphase promoting complex subunit 5 antibody, anaphase-promoting complex subunit 5 antibody, anaphase promoting complex subunit 5 L homeolog antibody, anaphase-promoting complex subunit antibody, anaphase-promoting complex subunit Apc5 antibody, ANAPC5 antibody, anapc5 antibody, LOC100093215 antibody, anapc5.L antibody, Anapc5 antibody, AT1G06590 antibody, apc5 antibody
Background
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. Alias Symbols: ANAPC5, APC5, Protein Interaction Partner: ANAPC2, UBE2S, UBC, ANAPC4, HECW2, LATS2, PHF8, SOX2, PTEN, CDC27, BACH1, TRIM33, ANAPC7, ANAPC15, CDH1, CDC20, PAXIP1, MDC1, TP53BP1, NOTCH1, ANAPC1, ANAPC13, CDC16, CDC23, FBXO5, USP37, CUL4A, SH3KBP1, E2F1, SMARCAD1, MAPK6, Gm9174, Anapc5, Mad2l1, Anap Protein Size: 219
Gene ID
51433
Pathways
M Phase
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