BMF antibody (N-Term)

Catalog No. ABIN5514556

Product Details anti-BMF Antibody

Target: BMF (Bcl2 Modifying Factor (BMF))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMF antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MEPSQCVEEL EDDVFQPEDG EPVTQPGSLL SADLFAQSLL DCPLSRLQLF

Predicted Reactivity: Cow: 92%, Dog: 92%, Goat: 85%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against BMF. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human BMF

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BMF

Target: BMF (Bcl2 Modifying Factor (BMF))

Alternative Name: BMF (BMF Products)

Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alias Symbols: BMF,

Protein Interaction Partner: SEC14L4, DYNLL2, TFIP11, REL, BCL2L2, BCL2L1, MCL1, BAG3, TCF12, NNMT, CXCL9, MAPK8, BCL2, DYNLL1, MYO5A, BCL2A1,

Protein Size: 129

Gene ID: 90427