CBR3 antibody (Middle Region)

Catalog No. ABIN5514608

The Rabbit Polyclonal anti-CBR3 antibody (ABIN5514608) specifically detects CBR3 in WB. The antibody is reactive with Human, Rat, Cow and Rabbit samples.

Quick Overview for CBR3 antibody (Middle Region) (ABIN5514608)

Target: CBR3 (Carbonyl Reductase 3 (CBR3))

Reactivity: Human, Rat, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBR3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CBR3 Antibody

Binding Specificity: Middle Region

Purpose: CBR3 Antibody - middle region

Sequence: CNELLPIMKP HGRVVNISSL QCLRAFENCS EDLQERFHSE TLTEGDLVDL

Predicted Reactivity: Cow: 79%, Human: 100%, Rabbit: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against CBR3. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human CBR3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45795-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CBR3

Target: CBR3 (Carbonyl Reductase 3 (CBR3))

Alternative Name: CBR3

Background:

Background Information: Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.

Gene Name: carbonyl reductase 3

Alternative Symbols: hCBR3, SDR21C2, HEL-S-25

Protein Name: Carbonyl reductase [NADPH] 3

Molecular Weight: 30kDa

Gene ID: 874

NCBI Accession: NP_001227

UniProt: O75828