CLIC2 antibody (N-Term)

Catalog No. ABIN5514643

The Rabbit Polyclonal anti-CLIC2 antibody is suitable to detect CLIC2 in samples from Human. It has been validated for WB.

Quick Overview for CLIC2 antibody (N-Term) (ABIN5514643)

Target: CLIC2 (Chloride Intracellular Channel 2 (CLIC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLIC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CLIC2 Antibody

Binding Specificity: N-Term

Sequence: TDFIKIEEFL EQTLAPPRYP HLSPKYKESF DVGCNLFAKF SAYIKNTQKE

Characteristics: This is a rabbit polyclonal antibody against CLIC2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CLIC2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CLIC2

Target: CLIC2 (Chloride Intracellular Channel 2 (CLIC2))

Alternative Name: CLIC2

Background: This gene encodes a chloride intracellular channel protein. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH , and regulation of cell volume. This protein may play a role in inhibiting the function of ryanodine receptor 2. A mutation in this gene is the cause of X-linked mental retardation-32.

Alias Symbols: CLIC2,

Protein Interaction Partner: UBC, FN1, NEDD4L, NEDD4, TRAPPC2,

Protein Size: 247

Gene ID: 1193

NCBI Accession: NP_001280

UniProt: O15247

Pathways: Negative Regulation of Transporter Activity