CX3CR1 antibody (C-Term)

Catalog No. ABIN5514661

The Rabbit Polyclonal anti-CX3CR1 antibody is suitable to detect CX3CR1 in samples from Human. It has been validated for WB.

Quick Overview for CX3CR1 antibody (C-Term) (ABIN5514661)

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CX3CR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CX3CR1 Antibody

Binding Specificity: C-Term

Sequence: EKFRRYLYHL YGKCLAVLCG RSVHVDFSSS ESQRSRHGSV LSSNFTYHTS

Characteristics: This is a rabbit polyclonal antibody against CX3CR1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CX3CR1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Alternative Name: CX3CR1

Background: Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.

Alias Symbols: CX3CR1, CMKBRL1, GPR13,

Protein Interaction Partner: CX3CL1,

Protein Size: 355

Gene ID: 1524

NCBI Accession: NP_001328

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin