DMRT1 antibody (Middle Region)

Catalog No. ABIN5514729

This Rabbit Polyclonal antibody specifically detects DMRT1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig and Horse.

Quick Overview for DMRT1 antibody (Middle Region) (ABIN5514729)

Target: DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMRT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DMRT1 Antibody

Binding Specificity: Middle Region

Sequence: GSPVKNSLRG LPGPYVPGQT GNQWQMKNME NRHAMSSQYR MHSYYPPPSY

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 77%, Rabbit: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against DMRT1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DMRT1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DMRT1

Target: DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))

Alternative Name: DMRT1

Background: This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.

Alias Symbols: DMT1, CT154

Protein Size: 215

Gene ID: 1761

NCBI Accession: NM_021951, NP_068770

UniProt: Q9Y5R6