DMRT1 antibody (Middle Region)

Catalog No. ABIN5514729

Product Details anti-DMRT1 Antibody

Target: DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMRT1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GSPVKNSLRG LPGPYVPGQT GNQWQMKNME NRHAMSSQYR MHSYYPPPSY

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 77%, Rabbit: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against DMRT1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DMRT1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DMRT1

Target: DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))

Alternative Name: DMRT1 (DMRT1 Products)

Synonyms: DMT1 antibody, DMRT1 antibody, zgc:136676 antibody, dmrt1 antibody, dmrt1-alpha antibody, dmt1 antibody, dmrt1-beta antibody, xdmrt1 antibody, doublesex and mab-3 related transcription factor 1 antibody, doublesex and mab-3 related transcription factor 1 L homeolog antibody, doublesex and mab-3 related transcription factor 1 S homeolog antibody, DMRT1 antibody, Dmrt1 antibody, dmrt1 antibody, dmrt1.L antibody, dmrt1.S antibody

Background: This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.

Alias Symbols: DMT1, CT154

Protein Size: 215

Gene ID: 1761

NCBI Accession: NM_021951, NP_068770

UniProt: Q9Y5R6