FEV antibody (C-Term)

Catalog No. ABIN5514763

The Rabbit Polyclonal anti-FEV antibody is suitable to detect FEV in samples from Human, Mouse, Rat, Cow, Guinea Pig, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for FEV antibody (C-Term) (ABIN5514763)

Target: FEV (FEV (ETS Oncogene Family) (FEV))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FEV antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FEV Antibody

Binding Specificity: C-Term

Purpose: FEV Antibody - C-terminal region

Sequence: APAGFSYWPG PGPAATAAAA TAALYPSPSL QPPPGPFGAV AAASHLGGHY

Predicted Reactivity: Cow: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against FEV. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human FEV

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35927-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FEV

Target: FEV (FEV (ETS Oncogene Family) (FEV))

Alternative Name: FEV

Background:

Background Information: This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.

Gene Name: FEV (ETS oncogene family)

Alternative Symbols: PET-1, HSRNAFEV

Protein Name: Protein FEV

Molecular Weight: 26kDa

Gene ID: 54738

NCBI Accession: NP_059991

UniProt: Q99581