FGF12 antibody (N-Term)

Catalog No. ABIN5514765

This Rabbit Polyclonal antibody specifically detects FGF12 in WB. It exhibits reactivity toward Human.

Quick Overview for FGF12 antibody (N-Term) (ABIN5514765)

Target: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FGF12 Antibody

Binding Specificity: N-Term

Purpose: FGF12 Antibody - N-terminal region

Sequence: QKRQARESNS DRVSASKRRS SPSKDGRSLC ERHVLGVFSK VRFCSGRKRP

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FGF12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP76155-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FGF12

Target: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Alternative Name: FGF12

Background:

Background Information: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene Name: Fibroblast growth factor 12

Alternative Symbols: FHF1, DEE47, EIEE47, FGF12B

Protein Name: fibroblast growth factor 12

Molecular Weight: 27 kDa

Gene ID: 2257

NCBI Accession: NP_004104

UniProt: P61328

Pathways: Negative Regulation of Transporter Activity