GDF10 antibody (C-Term)

Catalog No. ABIN5514834

This Rabbit Polyclonal antibody specifically detects GDF10 in WB. It exhibits reactivity toward Human.

Quick Overview for GDF10 antibody (C-Term) (ABIN5514834)

Target: GDF10 (Growth Differentiation Factor 10 (GDF10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GDF10 Antibody

Binding Specificity: C-Term

Purpose: GDF10 Antibody - C-terminal region

Sequence: LPGLDERPPR AHAQHFHKHQ LWPSPFRALK PRPGRKDRRK KGQEVFMAAS

Characteristics: This is a rabbit polyclonal antibody against BMP3B. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human BMP3B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP76188-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GDF10

Target: GDF10 (Growth Differentiation Factor 10 (GDF10))

Alternative Name: GDF10

Background:

Background Information: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of this gene is associated with oral cancer.

Gene Name: growth differentiation factor 10

Alternative Symbols: BIP, BMP3B, BMP-3b

Protein Name: growth/differentiation factor 10

Molecular Weight: 52kDa

Gene ID: 2662

NCBI Accession: NP_004953

UniProt: P55107