MYRIP antibody (Middle Region)

Catalog No. ABIN5514958

Product Details anti-MYRIP Antibody

Target: MYRIP (Myosin VIIA and Rab Interacting Protein (MYRIP))

Binding Specificity: Middle Region

Reactivity: Human, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYRIP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RRARLGSEEP SKEPSSPSAQ LRDLDTHQVS DDLSETDISN EARDPQTLTD

Predicted Reactivity: Dog: 86%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against MYRIP. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human MYRIP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MYRIP

Target: MYRIP (Myosin VIIA and Rab Interacting Protein (MYRIP))

Alternative Name: MYRIP (MYRIP Products)

Synonyms: SLAC2-C antibody, SLAC2C antibody, A230081N12Rik antibody, Slac2-c antibody, Slac2c antibody, MYRIP antibody, si:dkey-189e1.4 antibody, LOC100156583 antibody, myosin VIIA and Rab interacting protein antibody, MYRIP antibody, Myrip antibody, myrip antibody

Background: MYRIP is a rab effector protein involved in melanosome transport. It Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. It functions as a protein kinase A-anchoring protein (AKAP). It may act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release (By similarity).

Alias Symbols: MYRIP, SLAC2C,

Protein Interaction Partner: C1orf216, Dlg4, RAB27A, MYO7A,

Protein Size: 672

Gene ID: 25924

Pathways: Positive Regulation of Peptide Hormone Secretion