METTL1 antibody (C-Term)

Catalog No. ABIN5514969

This Rabbit Polyclonal antibody specifically detects METTL1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Saccharomyces cerevisiae.

Quick Overview for METTL1 antibody (C-Term) (ABIN5514969)

Target: METTL1 (Methyltransferase Like 1 (METTL1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-METTL1 Antibody

Binding Specificity: C-Term

Purpose: METTL1 Antibody - C-terminal region

Sequence: RIISPTLLAE YAYVLRVGGL VYTITDVLEL HDWMCTHFEE HPLFERVPLE

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%, Yeast: 90%

Characteristics: This is a rabbit polyclonal antibody against METTL1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human METTL1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48666-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for METTL1

Target: METTL1 (Methyltransferase Like 1 (METTL1))

Alternative Name: METTL1

Background:

Background Information: This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X.

Gene Name: methyltransferase like 1

Alternative Symbols: TRM8, TRMT8, C12orf1, YDL201w

Protein Name: tRNA (guanine-N(7)-)-methyltransferase

Molecular Weight: 30kDa

Gene ID: 4234

NCBI Accession: NP_075422

UniProt: Q9UBP6