NPY5R antibody (N-Term)

Catalog No. ABIN5514990

This Rabbit Polyclonal antibody specifically detects NPY5R in WB. It exhibits reactivity toward Human.

Quick Overview for NPY5R antibody (N-Term) (ABIN5514990)

Target: NPY5R (Neuropeptide Y Receptor Y5 (NPY5R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPY5R antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NPY5R Antibody

Binding Specificity: N-Term

Purpose: NPY5R Antibody - N-terminal region

Sequence: DEYYNKTLAT ENNTAATRNS DFPVWDDYKS SVDDLQYFLI GLYTFVSLLG

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N region of human NPY5R

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP76423-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NPY5R

Target: NPY5R (Neuropeptide Y Receptor Y5 (NPY5R))

Alternative Name: NPY5R

Background:

Background Information: The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene.

Gene Name: neuropeptide Y receptor Y5

Alternative Symbols: NPYR5, NPY5-R, NPYY5-R

Protein Name: neuropeptide Y receptor type 5

Molecular Weight: 49 kDa

Gene ID: 4889

NCBI Accession: NP_006165

UniProt: Q15761

Pathways: Feeding Behaviour