PDZRN3 antibody (Middle Region)

Catalog No. ABIN5515030

Product Details anti-PDZRN3 Antibody

Target: PDZRN3 (PDZ Domain Containing Ring Finger 3 (PDZRN3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDZRN3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DPYLLPEEHP SAHEYYDPND YIGDIHQEMD REELELEEVD LYRMNSQDKL

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PDZRN3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PDZRN3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDZRN3

Target: PDZRN3 (PDZ Domain Containing Ring Finger 3 (PDZRN3))

Alternative Name: PDZRN3 (PDZRN3 Products)

Synonyms: MGC80196 antibody, pdzrn3 antibody, LNX3 antibody, SEMACAP3 antibody, 1110020C07Rik antibody, AI429718 antibody, AL023082 antibody, Semcap3 antibody, PDZ domain containing ring finger 3 antibody, PDZ domain containing ring finger 3 L homeolog antibody, PDZ domain containing RING finger 3b antibody, E3 ubiquitin-protein ligase PDZRN3 antibody, PDZ domain containing RING finger 3 antibody, PDZRN3 antibody, pdzrn3.L antibody, pdzrn3b antibody, LOC100228989 antibody, pdzrn3 antibody, Pdzrn3 antibody

Background: PDZRN3 is an E3 ubiquitin-protein ligase. It plays an important role in regulating the surface level of MUSK on myotubes. It mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. It might contribute to terminal myogenic differentiation.

Alias Symbols: PDZRN3, KIAA1095, LNX3, SEMCAP3,

Protein Interaction Partner: Dlg4, LNX2, LNX1, UBE2D2, MUSK, PDZRN3, BMPR2, EFNB2,

Protein Size: 729

Gene ID: 23024

Pathways: Skeletal Muscle Fiber Development