RAB6A antibody (C-Term)

Catalog No. ABIN5515093

The Rabbit Polyclonal anti-RAB6A antibody is suitable to detect RAB6A in samples from Human. It has been validated for WB.

Quick Overview for RAB6A antibody (C-Term) (ABIN5515093)

Target: RAB6A (RAB6A, Member RAS Oncogene Family (RAB6A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB6A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAB6A Antibody

Binding Specificity: C-Term

Sequence: ERKAKELNVM FIETSAKAGY NVKQLFRRVA AALPGMESTQ DRSREDMIDI

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RAB6A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAB6A

Target: RAB6A (RAB6A, Member RAS Oncogene Family (RAB6A))

Alternative Name: RAB6A

Background: This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Alias Symbols: RAB6

Protein Size: 167

Gene ID: 5870

NCBI Accession: NM_001243718, NP_001230647

UniProt: P20340