ST5 antibody (N-Term)

Catalog No. ABIN5515162

The Rabbit Polyclonal anti-ST5 antibody is suitable to detect ST5 in samples from Human. It has been validated for WB.

Quick Overview for ST5 antibody (N-Term) (ABIN5515162)

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ST5 Antibody

Binding Specificity: N-Term

Purpose: ST5 Antibody - N-terminal region

Sequence: TSACRYPSHS SSRVLLKDRH PPAPSPQNPQ DPSPDTSPPT CPFKTASFGY

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ST5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP80591-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ST5

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Alternative Name: ST5

Background:

Background Information: This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.

Gene Name: suppression of tumorigenicity 5

Alternative Symbols: ST5, HTS1, p126

Protein Name: suppression of tumorigenicity 5 protein

Molecular Weight: 125 kDa

Gene ID: 6764

NCBI Accession: NP_005409

UniProt: P78524