TFB1M antibody (C-Term)

Catalog No. ABIN5515223

This anti-TFB1M antibody is a Rabbit Polyclonal antibody detecting TFB1M in WB. Suitable for Human.

Quick Overview for TFB1M antibody (C-Term) (ABIN5515223)

Target: TFB1M (Transcription Factor B1, Mitochondrial (TFB1M))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFB1M antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TFB1M Antibody

Binding Specificity: C-Term

Sequence: SISHFKSLCD VYRKMCDEDP QLFAYNFREE LKRRKSKNEE KEEDDAENYR

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TFB1M

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TFB1M

Target: TFB1M (Transcription Factor B1, Mitochondrial (TFB1M))

Alternative Name: TFB1M

Background: The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness (AID).

Alias Symbols: CGI75, mtTFB, CGI-75, mtTFB1

Protein Size: 346

Gene ID: 51106

NCBI Accession: NM_016020, NP_057104

UniProt: Q8WVM0