Tropomyosin 4 antibody (C-Term)

Catalog No. ABIN5515225

The Rabbit Polyclonal anti-Tropomyosin 4 antibody is suitable to detect Tropomyosin 4 in samples from Human. It has been validated for WB.

Quick Overview for Tropomyosin 4 antibody (C-Term) (ABIN5515225)

Target: Tropomyosin 4 (TPM4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tropomyosin 4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Tropomyosin 4 Antibody

Binding Specificity: C-Term

Sequence: TNNLKSLEAA SEKYSEKEDK YEEEIKLLSD KLKEAETRAE FAERTVAKLE

Characteristics: This is a rabbit polyclonal antibody against TPM4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TPM4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Tropomyosin 4

Target: Tropomyosin 4 (TPM4)

Alternative Name: TPM4

Background: This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: TPM4,

Protein Interaction Partner: UBC, TPM1, TP53, LNX1, MDM2, FASN, KIAA1598, SIRT1, CAP1, PARK2, UBD, HDAC8, PAN2, ATF2, TPM3P4, SRXN1, PRKCDBP, TXN2, CORO1C, DCTN2, G3BP1, TELO2, ZYX, TPM3, TPM2, SULT1A1, SNRNP70, SRSF2, PSMD2, PSMD1, PSMC2, PSMA6, PCMT1, MYH9, ILF3, ILF2, HNRNPK, DBN1

Protein Size: 284

Gene ID: 7171