HIP1R antibody (C-Term)

Catalog No. ABIN5515293

This Rabbit Polyclonal antibody specifically detects HIP1R in WB. It exhibits reactivity toward Human.

Quick Overview for HIP1R antibody (C-Term) (ABIN5515293)

Target: HIP1R (Huntingtin Interacting Protein 1 Related (HIP1R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIP1R antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HIP1R Antibody

Binding Specificity: C-Term

Purpose: HIP1R Antibody - C-terminal region

Sequence: RLQECSRTVN ERAANVVAST KSGQEQIEDR DTMDFSGLSL IKLKKQEMET

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HIP1R

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP80399-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HIP1R

Target: HIP1R (Huntingtin Interacting Protein 1 Related (HIP1R))

Alternative Name: HIP1R

Background:

Background Information: Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.

Gene Name: huntingtin interacting protein 1 related

Alternative Symbols: HIP3, HIP12, ILWEQ

Protein Name: huntingtin-interacting protein 1-related protein

Molecular Weight: 117 kDa

Gene ID: 9026

NCBI Accession: NP_001290026

UniProt: O75146