Zinc Finger Protein 650 (ZNF650) (C-Term) antibody

Catalog No. ABIN5515354

The Rabbit Polyclonal anti-Zinc Finger Protein 650 antibody is suitable to detect Zinc Finger Protein 650 in samples from Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for Zinc Finger Protein 650 (ZNF650) (C-Term) antibody (ABIN5515354)

Target: Zinc Finger Protein 650 (ZNF650)

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: C-Term

Purpose: UBR3 Antibody - C-terminal region

Sequence: SQNCGAGTGI FLLINASVII IIRGHRFCLW GSVYLDAHGE EDRDLRRGKP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human UBR3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43449-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Zinc Finger Protein 650 (ZNF650)

Alternative Name: UBR3

Background:

Background Information: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

Gene Name: ubiquitin protein ligase E3 component n-recognin 3 (putative)

Alternative Symbols: ZNF650

Protein Name: E3 ubiquitin-protein ligase UBR3

Molecular Weight: 394

Gene ID: 130507

UniProt: Q6ZT12

Pathways: Feeding Behaviour